The Process Development Blog

Small molecules still dominate FDA approvals, but rising stereochemical and solid-state complexity demands stronger CMC strategies for 2026 readiness.

For the synthesis & crystallization of APIs, Mixed Suspension Mixed Product Removal Crystallizers (MSMPRCs) can help address common issues in batch production.

Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)

[Webinar] Learn more about the use of Continuous Processing for Crystallization.

Discover the industry drivers for Continuous Processing and how it accelerates development and benefits your manufacturing strategy.

ATR-FTIR chemometric model provides real-time PAT feedback control for a flow acylation process, predicting species abundance within 3 area% of offline analysis.

Computational solvent screening narrows 70 candidates to under 10 in 2–3 days, with solubility predictions within 20% of experiment—applied to API crystal morphology design.

[WEBINAR] In this webinar, we share methods to screen and optimize reactions under extreme time constraints using flow chemistry setups integrated with PAT.