The Process Development Blog

Eóin Bourke shows how APC moved an ADC bioconjugation from batch to a scalable continuous flow process using kinetics, CFD and Dynochem modelling.

Discover how Computational Fluid Dynamics (CFD) helps de-risk scale-up and optimize biopharmaceutical manufacturing. Learn how CFD reveals hidden mixing dynamics, supports tech transfer, improves efficiency, and ensures regulatory-ready process insights.

Explore peptide crystallization techniques including solvent screening, co-crystallization, and in-silico modelling to overcome scale-up challenges in peptide manufacturing.

CFD, discrete element method, and mechanistic modelling enable virtual transfection and transduction optimisation for cell and gene therapy process development.

A lack of process understanding & control leads to: inability to scale, product quality drift, & costly delays from batch failures & regulatory concerns

[Webinar] Explore the benefits of applying CFD to better understand your process.

CFD modelling of bioreactor mixing environments enables vaccine scale-up with two-thirds fewer experiments, eliminating stepwise progression between vessel sizes.

Harnessing the power of CFD to optimize process equipment cleaning protocols

Learn how a good numerical modeling strategy can help scale-up of single-use bioreactors.

Computational fluid dynamics virtual experiments let pharma and biotech teams solve process challenges before entering the lab, cutting development time and resource use.