[ARTICLE] Indium chloride catalysed benzyl bromination using continuous flow technology
Thankappan, H., Burke, C., & Glennon, B. (2023). Indium chloride catalysed benzyl bromination using continuous flow technology. Organic &Amp; Biomolecular Chemistry. https://doi.org/10.1039/d2ob01840c
This report describes the development of a water-tolerant green catalyst for benzyl bromination. The catalyst, indium chloride, exhibits high catalytic activity with a variety of toluene derivatives in continuous flow. Good yields (59–77%) were obtained in all the cases. Improved selectivity was observed under flow conditions, when compared to batch operation.