This paper explores the development of a chromatography-based platform process for adeno-associated virus (AAV) purification, focusing on exploiting AAV characteristics and addressing impurities to enable scalable and standardized gene therapy manufacturing.
Decoupling process development from manufacturing enhances control, flexibility and innovation - accelerating time to market and reducing risks in pharmaceutical development.
We’ve curated a list of key crystallization publications from the past 25 years, showcasing the research and breakthroughs that have defined our approach and expertise. These publications represent the culmination of decades of innovative work by APC’s crystallization experts, illustrating our ongoing impact in this field.
This study introduces a hybrid method combining the COSMO-RS model with machine learning to predict aqueous solubility at room temperature.
Explore these innovative approaches undertaken by APC in addressing the challenges of peptide crystallization .
Decentralized manufacturing in pharma, driven by ATMPs, is now extending to traditional large & small molecule medicines, transforming development & production.
At APC and VLE Therapeutics, we take great pride in our role in advancing the development of therapeutics for rare diseases.
Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)
Automated assembly of hybrid dynamic models for CHO cell culture processes. Doyle, K., Tsopanoglou, A., Fejér, A., Glennon, B., & del Val, I. J. (2023)