The Process Development Blog

In this study, the final purification step of a mAb was resulting in significant yield loss (up to 50%). Learn how experts redefined this problematic process.

Brendan Roche PhD will present 'Development strategies to keep pace with increasing stereochemical complexity of drug candidates', reviewing how experts leverage the power of PAT, modelling, and other cutting-edge techniques which can be applied to key unit operations (e.g. crystallization, isolation etc.) of enantiomers and diastereomers of varying stereochemical complexity.

[WEBINAR] Accelerate development without comprising on quality! Dr Hasbullah Daud discusses how - using PAT, modelling, & cutting-edge analytical techniques.

Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)

Automated assembly of hybrid dynamic models for CHO cell culture processes. Doyle, K., Tsopanoglou, A., Fejér, A., Glennon, B., & del Val, I. J. (2023)

APC & VLE founders Mark Barrett & Brian Glennon, receive Pharma Leader award for their innovative global centre of excellence in process dev & manufacturing.

Learn more about Nobel-prize winner Barry Sharpless and his impact on modern chemistry.

[WEBINAR] Learn how mechanistic modelling + CFD to understand and optimize transfection and transduction efficiency can increase yield and lower costs.

APC's information partnership approach offers in-depth process understanding, reducing outsourcing dependency.

A lack of process understanding & control leads to: inability to scale, product quality drift, & costly delays from batch failures & regulatory concerns