The Process Development Blog

The Medicine Accelerator joins Manufacturing Day Ireland on 3 October, hosting future innovators to explore careers in science, technology, and advanced manufacturing.

This on-demand webinar from APC explores how Crystallization-Induced Diastereomeric Transformation, or CIDT, can improve diastereomeric salt crystallization for chiral resolution. The session covers solubility behavior, phase relationships, counterion selection, solvent choice, solid-state control, and analytical strategies for improving enantiomer separation. It is relevant for pharmaceutical development teams working on chiral molecules, double salts, crystallization process design, yield improvement, purity optimization, scale-up, and enantiopure compound production.

See how CrysAI™ applies deep learning to crystallization and cell imaging—automating segmentation, improving reproducibility, and scaling insight.

APC & VLE Therapeutics is looking forward to seeing you at this CLS event in San Diego which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

Building on this foundation, APC announces a strategic partnership with METTLER TOLEDO AutoChem, a global leader in automated reactor technology, process analytical tools (PAT), and chemical development software platforms. Together, the partnership seeks to build a fully integrated digital development environment—advancing how data, decisions, and design converge across the full CMC lifecycle.

This paper explores the development of a chromatography-based platform process for adeno-associated virus (AAV) purification, focusing on exploiting AAV characteristics and addressing impurities to enable scalable and standardized gene therapy manufacturing.

APC & VLE Therapeutics is looking forward to seeing you at Biomanufacturing World Summit, in San Diego which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

APC & VLE Therapeutics is looking forward to seeing you at AIChE, in Boston which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

APC & VLE Therapeutics is looking forward to seeing you at World Vaccine Congress, in Amsterdam which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

The Medicine Accelerator is expanding its digital business with strategic new roles to scale iAchieve®—a first-of-its-kind digital CMC platform built on 100,000s of expert-led experiments and thousands of contextualized programs—to accelerate medicine development and manufacturing globally.