The Process Development Blog

A Chinese Hamster Ovary (CHO) mammalian cell process moved to a PAT-enabled continuous feed strategy to prevent nutrient loss & stabilize the macroenvironment.

For the synthesis & crystallization of APIs, Mixed Suspension Mixed Product Removal Crystallizers (MSMPRCs) can help address common issues in batch production.

[WEBINAR] Experts review challenges, proven strategies for tech transfer, & an unique approach using digitalization, process optimization, & risk management.

With 68% of 2022 FDA small molecule approvals containing chiral centres, structured enantioselective crystallisation strategies are essential for modern drug development.

In this study, the final purification step of a mAb was resulting in significant yield loss (up to 50%). Learn how experts redefined this problematic process.

On-demand webinar on MVA-based viral vector development covering purification technology selection, scalable platform approaches, and novel analytical characterisation methods.

Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)

Automated assembly of hybrid dynamic models for CHO cell culture processes. Doyle, K., Tsopanoglou, A., Fejér, A., Glennon, B., & del Val, I. J. (2023)

APC and VLE founders Mark Barrett and Brian Glennon received the 2022 Pharma Leader award, recognising growth from 2 to 270 staff and development of over 400 medicines.

[WEBINAR] Learn how mechanistic modelling + CFD to understand and optimize transfection and transduction efficiency can increase yield and lower costs.