[PANEL DISCUSSION] Data Visibility & Ownership when Working with External Partners
[PANEL DISCUSSION] CMC data is often fragmented, siloed and lacks context - causing regulatory bottlenecks, manufacturing delays & quality issues.
Cutting edge process development insights and news from APC.
[PANEL DISCUSSION] CMC data is often fragmented, siloed and lacks context - causing regulatory bottlenecks, manufacturing delays & quality issues.
Using data-rich experimentation and mixing models, which leverage CFD, a right-first scale up of the new process was achieved within the yield improvements translating directly back to the plant.
A Chinese Hamster Ovary (CHO) mammalian cell process moved to a PAT-enabled continuous feed strategy to prevent nutrient loss & stabilize the macroenvironment.
For the synthesis & crystallization of APIs, Mixed Suspension Mixed Product Removal Crystallizers (MSMPRCs) can help address common issues in batch production.
[WEBINAR] Experts review challenges, proven strategies for tech transfer, & an unique approach using digitalization, process optimization, & risk management.
[Webinar] Dr Brendan Roche reviews engineering strategies for unit ops (crystallization, isolation, etc.) when manufacturing molecules w/ complex stereochemistry.
In this study, the final purification step of a mAb was resulting in significant yield loss (up to 50%). Learn how experts redefined this problematic process.
[WEBINAR] Accelerate development without comprising on quality! Dr Hasbullah Daud discusses how - using PAT, modelling, & cutting-edge analytical techniques.
Automated assembly of hybrid dynamic models for CHO cell culture processes. Doyle, K., Tsopanoglou, A., Fejér, A., Glennon, B., & del Val, I. J. (2023)
Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)