The Process Development Blog

[PANEL DISCUSSION] CMC data is often fragmented, siloed and lacks context - causing regulatory bottlenecks, manufacturing delays & quality issues.

Using data-rich experimentation and mixing models, which leverage CFD, a right-first scale up of the new process was achieved within the yield improvements translating directly back to the plant.

[WEBINAR] Learn how mechanistic modelling + CFD to understand and optimize transfection and transduction efficiency can increase yield and lower costs.

A lack of process understanding & control leads to: inability to scale, product quality drift, & costly delays from batch failures & regulatory concerns

Learn how a good numerical modeling strategy can help scale-up of single-use bioreactors.

Our expert, Dr. Jacek Zeglinski talks about the various challenges which drug substance developers face when seeking to develop material suitable for tabletting

[WEBINAR] In this webinar, we share methods to screen and optimize reactions under extreme time constraints using flow chemistry setups integrated with PAT.

Predicting the percolation threshold, using statistical models or experimentation, is an evidence-based approach that can get solid dosage forms designed faster.

Computational methods play an increasingly important role in all stages of drug development and when used judiciously can help accelerate the timelines required to get over various process and manufacturing hurdles.