The Process Development Blog

October 22 2025: Minister for Further and Higher Education, Research, Innovation and Science, James Lawless TD has today announced a €2million co-funded investment by APC Ltd and Research Ireland. To be funded for the next five years, TRANS-AM is a collaborative research partnership between APC Ltd, the National Institute for Bioprocessing Research and Training (NIBRT), and University College Dublin (UCD), and is focused on advanced biotherapeutics.

Discover how Computational Fluid Dynamics (CFD) helps de-risk scale-up and optimize biopharmaceutical manufacturing. Learn how CFD reveals hidden mixing dynamics, supports tech transfer, improves efficiency, and ensures regulatory-ready process insights.

The Medicine Accelerator joins Manufacturing Day Ireland on 3 October, hosting future innovators to explore careers in science, technology, and advanced manufacturing.

See how CrysAI™ applies deep learning to crystallization and cell imaging—automating segmentation, improving reproducibility, and scaling insight.

APC & VLE Therapeutics is looking forward to seeing you at this CLS event in San Diego which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

Building on this foundation, APC announces a strategic partnership with METTLER TOLEDO AutoChem, a global leader in automated reactor technology, process analytical tools (PAT), and chemical development software platforms. Together, the partnership seeks to build a fully integrated digital development environment—advancing how data, decisions, and design converge across the full CMC lifecycle.

This paper explores the development of a chromatography-based platform process for adeno-associated virus (AAV) purification, focusing on exploiting AAV characteristics and addressing impurities to enable scalable and standardized gene therapy manufacturing.

APC & VLE Therapeutics is looking forward to seeing you at Biomanufacturing World Summit, in San Diego which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.

APC & VLE Therapeutics is looking forward to seeing you at AIChE, in Boston which brings together upstream, downstream, bioproduction, analytical, and formulation professionals to advance the manufacture, quality, and control of biological and genetic therapies.