Case Studies
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How to access differentiated API particle populations through continuous technologies
For the synthesis & crystallization of APIs, Mixed Suspension Mixed Product Removal Crystallizers (MSMPRCs) can help address common issues in batch production.
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The importance of choosing the correct chromatography resin
In this study, the final purification step of a mAb was resulting in significant yield loss (up to 50%). Learn how experts redefined this problematic process.
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A HTE + PAT Strategy for Accelerated Bio-process Development
A lack of process understanding & control leads to: inability to scale, product quality drift, & costly delays from batch failures & regulatory concerns
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The 4 Essential Elements of a Successful ATMP Development Plan
Tech transfer of Advanced Therapy Medicinal Products (ATMPs) presents additional challenges beyond those faced when transferring more traditional biologics.
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How to Use Computational Approaches to Improve Powder Forms
Our expert, Dr. Jacek Zeglinski talks about the various challenges which drug substance developers face when seeking to develop material suitable for tabletting
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A Holistic View to Particle Sizing
Particle sizing is hugely important. However, it is laden with complexities and there is a general misunderstanding of the techniques used.
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Fixing formulation problems through particle shape control
Subtle changes in particle size, shape, & distribution can have a major impact on pharma solubility and stability and cause flow and formulation issues.