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Process Advancing Medicine
  • Dublin
  • Boston
  • Worldwide

Chromatography

High yield and purity | ÄKTA™ technology | ion exchange and affinity | purification and isolation | impurity removal and polishing | ChromX modeling | upstream integration 

Chromatography is the cornerstone of our downstream process development approach where we strive to isolate and purify your product in a manner that delivers high yields and purity. 

We build design spaces around ion exchange and affinity chromatography platforms and we use our ÄKTA™ technology infrastructure to screen resins and run powerful DOEs that gather the most information, using the least material, in the shortest space of time. Throughout downstream development we constantly evaluate the best approach capture, concentrate and stabilize products before removing impurities and polishing the final product.

We also leverage chromatography modeling packages, like ChromX, to obtain process understanding earlier in development, and to minimize the number of experiments we run in the lab. This approach, combined with our downstream expertise and smart experimental strategies, ensure that downstream development can keep up with upstream breakthroughs.