CRLs often stem from hidden knowledge gaps. Discover how iAchieve® turns tacit expertise into traceable CMC logic to strengthen submissions and reduce risk.

This paper explores the development of a chromatography-based platform process for adeno-associated virus (AAV) purification, focusing on exploiting AAV characteristics and addressing impurities to enable scalable and standardized gene therapy manufacturing.

Decoupling process development from manufacturing gives pharma companies portable, well-understood processes that transfer across facilities and reduce FDA regulatory risk.

We’ve curated a list of key crystallization publications from the past 25 years, showcasing the research and breakthroughs that have defined our approach and expertise. These publications represent the culmination of decades of innovative work by APC’s crystallization experts, illustrating our ongoing impact in this field.

This study introduces a hybrid method combining the COSMO-RS model with machine learning to predict aqueous solubility at room temperature.

Explore peptide crystallization techniques including solvent screening, co-crystallization, and in-silico modelling to overcome scale-up challenges in peptide manufacturing.

Decentralized manufacturing in pharma, driven by ATMPs, is now extending to traditional large & small molecule medicines, transforming development & production.

APC and VLE mark Rare Disease Day 2024 by reaffirming their commitment to accelerating therapeutics for conditions where only 5% have approved treatments.

Indium chloride catalysed benzyl bromination using continuous flow technology. Thankappan, H., Burke, C., & Glennon, B. (2023)