Our team of PhD chemistry experts deliver scientific breakthroughs every time they optimize stoichiometry, build a kinetic profile, purge an impurity, recover a catalyst or choose the perfect process parameter.

We combine our vast experience with key technology platforms to troubleshoot reactions, improving yield and purity and productivity quickly.

We take promising synthetic routes and wrap world-class processes around them, collaborating with our clients to understand the clinical landscape and advance programs using fit for purpose development work.

Every time a reaction is quenched, our PhD chemists strive to fundamentally understand where impurities are going and how product yield can be improved, always thinking ahead to how work-up will be accomplished at scale.

APC can screen reaction conditions 60% faster than usual, using continuous flow rigs configured to run at steady state across a massive set of parameters, slashing development time and finding conditions that are perfect for your chemistry.

An elegant extraction designed well, can scale-up quickly, save valuable months, during process characterization or manufacturing introduction.

We are constantly determining the impact of stoichiometry on reaction progression and impurity formation and we collect time course reaction information to develop kinetic models that help us choose the correct process paramaters for a facile scale-up.

We combine FMEA risk assessments, CPP classification, model supported design of PARs and DoEs to fully characterize late stage processes so commercial introduction happens flawlessly.

Combining reaction modeling with DoEs uncovers the most important parts of a design space in hours, not weeks, shortening process characterization and identifying the key scale-up challenge quicker than before.

Our PAT infrastructure is unrivalled across our industry and is only matched by the expertise our people have in deploying it to monitor reactions, find intermediates, build kinetic profiles and study impurities.

Our team of PhD experts take early phase precipitations and transform them into flawless crystallizations, selecting perfect solvents, choosing the right process parameters and leveraging the unique thermodynamic and kinetic landscape of each process to target the product attributes needed.

APC has built a crystallization design platform combining molecular design, thermodynamic modeling and data rich experimentation to transform crystallization and isolation processes, for intermediates and APIs, in weeks, not months.

We developed a solvent selection platform that combines breakthrough modeling with smart experimentation to pick solvents that are perfect-for-purpose and in 80% less time than traditional methods.

Our crystallization processes make scaling easier because we use every single experiment to build a scientific underpinning, and we simulate manufacturing environments using advanced modeling, thousands of times, before embarking on tech transfer.

At APC, we combine in silico modeling with experimental platforms to select a salt, co-crystal or polymorph that will have far-reaching benefits for patients in terms of product stability, pharmacokinetic performance and bioavailability.

APC's team of particle engineers produce higher purities and better yields, and deliver particle properties like size, shape and polymorphic form, that make filtration and drying easier, while helping formulators unlock new options for patient delivery.

Exquisite particles, with optimized size and shape, designed in the lab need to be delivered at scale, so we built a scale-up platform combining engineering calculations with computational fluid dynamics, to simulate manufacturing equipment and conditions easily.

We use continuous crystallization to engineer particles that cannot be delivered using batch approaches, targeting parts of the phase diagram kinetic landscape, that cannot be accessed using batch approaches.

At APC we design great crystals and turn them into perfect powders, by developing filtration, washing and drying steps from the ground up, using the latest science-based approaches.

At APC, our process development experts are co-located with our world-class analytical team, working together to create, transfer and improve every method needed to chaarcterize reactants, impurities, intermediates and products faster than anyone else.

Fast development requires an analytical strategy that can measure powder properties like size, shape, porosity and density quickly, so we built a best-in-class analytical infrastructure co-located with our process development labs that takes turnaround times down to minutes.

95% of the methods needed to run a synthetic process development program are available in-house meaning our process development experts never need to wait for the insights they need to keep development on track.

Our goal is to make working with us effortless, and our dedicated team of project managers make this happen, asking the right questions, keeping the end goal in mind, and constantly driving us and you to deliver.

Led by a dedicated and brilliant team – 90% of us are PhDs with years of manufacturing experience – your medicine is in the best hands from project scoping to CMO hand-off and all points in between.

We learn and grow together with our clients, deepening our skills, finding new breakthroughs and thriving in a process development environment where every day is different.

As perpetual innovators and disruptors in the process development space, we're constantly cultivating new talent and enhancing our capabilities.