Careers

APC Ltd is an award-winning and rapidly growing science- and technology-driven pharmaceutical process research company. In the space of 5 years, we have pioneered innovation in the sector and we now partner with 8 of the top-10 pharma and 5 of the top-10 biotech firms in the world.

From our world-class facility, we offer specialised chemical and process engineering solutions. Powered by novel technology and world-class scientific research, we help companies accelerate the development & launch of their medicines.

Our rapid growth has come from a commitment to excellence, a drive to innovate and the desire to develop a challenging, creative and rewarding environment for our team. If you are interested in a career focused on technical innovation, technology design and impact, we would love to hear from you.

Current Open Roles in APC:

 

Quality Officer

Role Purpose

Responsible for ensuring that the technical processes meet the best in class Quality standards through provision of Quality support to APC Technical Operations ensuring a high standard of awareness, understanding and compliance of Quality SOPs and processes.

 

Key Responsibilities

Quality Management System

  • Develop, enhance and maintain the Quality Assurance programme to meet best in class standards.
  • Enhance the regulatory understanding and capability of the team
  • Ensure the organisation meets its statutory obligations in all Quality areas and supports the fostering of a workplace which focuses on ‘right first time’.
  • Ensure all SOPs, forms, logs, protocols and summary reports are completed and reviewed against Quality standards.  Issue laboratory notebooks and equipment logbooks as required.
  • Support the development and implementation of QMS programme across the organisation.
  • Identify and implement training to ensure efficient and effective completion of all Quality related training.
  • Ensure that all quality SOPs and programmes are adhered to and are regularly reviewed, updated and communicated.
  • Prepare Quality compliance metrics as required.
  • Ensure that all CAPAs and deviations are documented, investigated and recommended improvements implemented.

Audit Readiness & Continuous Improvement

  • Provide subject matter expertise to Technical Operations on various Quality related topics.
  • Support any external Quality audits with co-ordination of audit activities and action plans.
  • Conduct internal Quality audits e.g. walk through audits, system audits, report issuance, CAPA follow-up and closure.  Ensure that follow-up actions are completed.
  • Ensure compliance of Quality and use analytics to measure compliance across the organisation.
  • Establish a structured programme of Quality training across the organisation and ensure accurate training records are maintained.
  • Facilitates ‘as is’ mapping and root cause analysis.  Use continuous improvement tools to instigate actions for improvements.
  • Adhere to business processes as required.

Collaboration & Engagement

  • Provide Quality oversight for assigned projects within Technical operations.  Actively participate in projects by attending meetings (internal and external) and project updates, perform quality review of laboratory notebooks, technical data and the final technical reports
  • Contribute to and participate in the After-Action Review (AAR) meetings.
  • Prepare and deliver quality training materials to colleagues.
  • Share information, suggestions and observations to create consistency in Quality standards across the organisation.
  • Collaborate with HR and Training on LMS and training activities.
  • Participate in relevant forums e.g. QMS/SMS, training, equipment as required to improve awareness of Quality.

 

Key Competencies

  • Excellent organisational skills and ability to prioritise.
  • Flexible and be able to adapt within a changing environment.
  • Excellent communication skills with the ability to work cross-functionally.
  • Excellent oral and written communication and planning skills.

 

Required Experience

  • Required: Degree level or equivalent in life sciences.
  • Desirable: Inclusion of Quality related subject in qualification.
  • 3-4 years’ experience working in the pharma/biopharma industry or R&D environment.
  • Good working knowledge of implementing and using continuous improvement tools.
  • Experience with implementation of corrective action programmes.
  • Experience of development, implementation and management of Quality Management systems.

 

Skills & Knowledge  

  • Good working knowledge of MS Office.
  • Excellent technical report writing skills.
  • Excellent attention to detail.
  • Ability to work autonomously or as part of a diverse team.
  • Regulatory experience in a GMP environment would be advantageous

 

If you believe you have the capability required and the interest in being part of this dynamic rapidly growing organisation, we would like to talk to you.  

The closing date for applications is Monday 24th January 2019.

 

Salary

Negotiable

 

Apply Here

 

Analytical Scientist 2

Principal Responsibilities:

The role of the Analytical Scientist II is to provide analytical support, guidance and oversight to bio/pharmaceutical process research and development projects and activities within APC’s large/small molecule commercial projects portfolio. The Analytical Scientist II will work closely with groups of engineers, chemists and other analytical scientist, who are in collaboration on research projects as part of a team to enable the successful deployment and execution of APC’s ACHIEVE and BIOACHIEVE platforms. The Analytical Scientist II will also provide mentorship, where applicable, to more junior analytical scientist and represent the APC values in all day to day interactions, both internally and externally.

 

Laboratory Support:

  • Responsible for sample preparation, running, data analysis and reporting of results of analytical analysis for multiple R&D projects in accordance with supplied client guidelines/protocols.
  • Work collaboratively with project team (scientists/engineers) to ensure both in process and final product analytical testing is carried out in a timely manner to ensure project deadlines are achieved.
  • Carry out a technical transfer of analytical project methods and clarify any issues with AS3 and/or Senior AS internally and/or AS externally as required at the beginning of projects, highlight any potential issues/questions that may need to be addressed.
  • Carries out equipment ownership responsibilities for assigned equipment, problem solves, develops solutions for issues and escalates to AS3 or Senior AS as required.
  • Demonstrate competency in the running and analysis of different analytical techniques e.g. HPLC, UPLC, GC (HS), DSC, TGA, XRD, Malvern, SEM, microscopy electrophoretic techniques such as capillary electrophoresis, imaged CIEF, SDS-PAGE, 2D-PAGE and Western blotting, HPLC/UPLC methods for protein characterisation including reversed phase impurities assays, peptide mapping, glycan analysis, aggregates analysis (SEC) and charged variant analysis, immunoassays (ELISA), qPCR and flow cytometry, and other related analytical equipment as necessary for each project.
  • Proficiency in at least one analytical area e.g. wet chemistry techniques, Chromatography, solid state analytics, PAT (Process Analytical Technology), ELISAs, electrophoretic techniques, protein characterisation.
  • Prepare technical presentations and report material, and present the issues, results and project progress across multiple clients as required. Ensure all data compiled meets GLP standards.
  • Ensure the operation to GLP standard within a R&D laboratory is maintained at all times.

 

Additional Responsibilities:

  • Ensure that safe working practices are adhered to in line with relevant local and legal requirements.
  • Based on needs, develop and introduce new techniques, methods and processes to improve business effectiveness.
  • Support the training and development of team members – scientists/engineers
  • Ensure all laboratory procedures are adhered to e.g. removal of expired material and reagents, disposal of waste, movement of client samples etc.
  • Liaise with the Laboratory Manager as required to maintain a shared awareness of the issues requiring attention within the laboratories.

 

Minimum Experience:

You will have:

  • Minimum of 1-2 + years industry experience in pharmaceutical process research and development (if PhD qualified); or
  • Minimum of 3-4 + years industry experience (if Masters qualified); or
  • Minimum of 4 + years industry experience (if Bachelors qualified).

 

Desired Experience:

  • PhD in Analytical Chemistry/Analytical Science or related area or
  • Masters in Analytical Chemistry/Analytical Science or related area; or
  • Bachelors in Analytical Chemistry/Analytical Science or related area.

 

How to Apply:

Suitable candidates should submit a CV and a Cover Letter by close of business, Friday 11th January 2019 via the below link.

The salary is negotiable and dependent on the experience of the successful candidate.

 

Apply Here

Bioprocess R&D Scientist – Engineer

Principal Duties and Objectives

  • Operate to GLP standards within a R&D laboratory
  • Provide R&D laboratory support across the APC Bioprocess Development Group through collaboration with other scientists and engineers, both internally and externally
  • Working within a research team to plan, organise and deliver R&D biopharmaceutical research projects
  • Monitor, develop and optimize upstream and downstream processes
  • Perform analytical characterization of isolated materials
  • Develop biopharmaceutical scale-up and optimization strategies
  • Based on needs, develop and introduce new techniques, methods and processes to improve business effectiveness
  • Prepare technical presentations and report material
  • Present the issues, results and project progress to client companies and management

 

Minimum Requirements

  • PhD in Biochemistry, Molecular Biology, Bioprocess Engineering or related area with a minimum of 1 – 2 year’s industry experience in process development or a MSc in Biochemistry, Molecular Biology or ME Chemical Engineering or related area with a minimum of 3-4 + year’s industry experience in process development
  • Experienced in biopharmaceutical analysis
  • Ability to work in a dynamic and multidisciplinary environment
  • Self-motivated with demonstrated project management skills
  • Excellent technical communications skills, with previous technical presentation experience
  • Ability to disseminate information to research team and directors

 

Desirable Skills

  • Demonstrated use of PAT
  • Understanding of kinetics of bioprocesses, process modelling
  • Good understanding of DoE and QbD for process development
  • Experience with scale-up techniques for processes from laboratory to plant scale

  

How to Apply:

Suitable candidates should submit a CV and a Cover Letter by close of business, Friday 11th January 2019 via the below link.

The salary is negotiable and dependent on the experience of the successful candidate.

 

Apply Here

Process Development Scientist – Engineer

Principal Duties and Objectives

R&D Pharmaceutical Research Project Support

  • Working within a research team, co-ordinate the planning, organising and delivery of R&D pharmaceutical research projects.
  • Prepare and review technical presentations and report material, and present the issues, results and project progress to clients as required.
  • Based on project needs, develop and introduce new techniques, methods and processes to improve business effectiveness.
  • Generate ideas and suggestions on how to improve technical capabilities.
  • Coach mentor and train junior team members.
  • Represent the organisation at conference events.

 

Laboratory Support

  • Provide R&D laboratory support across the organisation through collaboration with scientists and engineers, both internally and externally.
  • Ensure that operation to GLP standard within a R&D laboratory is maintained at all times.
  • Monitor, develop and optimise pharmaceutical reaction and purification unit processes.
  • Develop pharmaceutical scale-up and optimisation strategies.
  • Perform analytical characterisation of isolated materials.
  • Solve complex technical problems and take responsibility for implementing the solutions.
  • Ensure that safe working practices are adhered to in line with relevant local and legal requirements.
  • Liaise with the Laboratory Manager as required to maintain a shared awareness of the issues requiring attention within the laboratories.

 

Minimum Requirements

  • 4-6 years post degree or 3-4 years post grad (M.Sc. or Ph.D.) qualification
  • Experienced in pharmaceutical Engineering / Chemistry analysis
  • Ability to work in a dynamic and multidisciplinary environment
  • Self-motivated with demonstrated project management skills
  • Excellent technical communications skills, with previous technical presentation experience
  • Ability to disseminate information to research team and directors

 

Desirable Skills

  • Demonstrated use of PAT in reaction and/or crystallization monitoring
  • Understanding of kinetics of reactions, process/reaction modelling
  • Good understanding of DoE and QbD for process development
  • Experience with scale-up techniques for processes from laboratory to plant scale

 

How to Apply:

Suitable candidates should submit a CV and a Cover Letter by close of business, Friday 11th January 2019 via the below link.

The salary is negotiable and dependent on the experience of the successful candidate.

 

Apply Here

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